Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938749 | 0.85 | ALDH1A1 (0.40) | KDM4ESMN1; SMN2ALDH1A1TSHRPOLB | |
| SCHEMBL3934765 | 0.77 | KIF11 (0.39) | KDM4ESMN1; SMN2ALDH1A1POLBHSD17B10 | |
| SCHEMBL10271522 | 0.75 | KIF11 (0.46) | KDM4ESMN1; SMN2ALDH1A1POLBHSD17B10 | |
| SCHEMBL20543670 | 0.73 | EPHX2 (0.52) | KDM4EALDH1A1EPHX2PPARG | |
| Hydrochloric Acid SCHEMBL31407479 | 0.71 | KDM4E (0.42) | KDM4ESMN1; SMN2ALDH1A1CTNNB1WNT3A | |
| SCHEMBL3945810 | 0.71 | KDM4E (0.42) | KDM4ESMN1; SMN2ALDH1A1TSHRPOLB | |
| SCHEMBL16252832 | 0.70 | CTNNB1 (0.44) | KDM4ESMN1; SMN2ALDH1A1POLBHSD17B10 | |
| SCHEMBL6112218 | 0.70 | CTNNB1 (0.41) | KDM4ESMN1; SMN2ALDH1A1POLBHSD17B10 | |
| SCHEMBL16240695 | 0.69 | CTNNB1 (0.45) | KDM4ESMN1; SMN2ALDH1A1POLBHSD17B10 | |
| SCHEMBL27600648 | 0.68 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1MAPK1EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082372-A1 | Arylmethylene Substituted N-Acyl-Beta-Amino Alcohols | BAYER SCHERING PHARMA AG (DE) | 2009-03-26 | — | — | US | disclosed |
| WO-2009013354-A1 | ARYLMETHYLENE SUBSTITUTED N-ACYL-β-AMINO ALCOHOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082372-A1 | Arylmethylene Substituted N-Acyl-Beta-Amino Alcohols | FSHR, SHBG, NAT1 | KDM4E 1126/4885SMN1; SMN2 2238/4885ALDH1A1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.