Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.95 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.95 |
| ▸ | CES2 | O00748 | 2/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL3934174 | 1.00 | LMNA (0.95) | LMNAMAPK1CES2CES1SRC | |
| Mandelic Acid SCHEMBL21647917 | 0.97 | LMNA (1.00) | LMNAMAPK1CES2CES1SRC | |
| Mandelic Acid SCHEMBL165161 | 0.97 | LMNA (1.00) | LMNAMAPK1CES2CES1SRC | |
| Mandelic Acid SCHEMBL29777368 | 0.97 | LMNA (1.00) | LMNAMAPK1CES2CES1SRC | |
| Mandelic Acid SCHEMBL255601 | 0.97 | LMNA (1.00) | LMNAMAPK1CES2CES1SRC | |
| Mandelic Acid SCHEMBL1050 | 0.97 | LMNA (1.00) | LMNAMAPK1CES2CES1SRC | |
| Mandelic Acid SCHEMBL5313046 | 0.97 | LMNA (1.00) | LMNAMAPK1CES2CES1SRC | |
| Mandelic Acid SCHEMBL1374278 | 0.95 | LMNA (0.95) | LMNAMAPK1CES2CES1SRC | |
| Mandelic Acid SCHEMBL9185770 | 0.95 | LMNA (0.95) | LMNAMAPK1CES2CES1SRC | |
| Mandelic Acid SCHEMBL9051446 | 0.95 | LMNA (0.95) | LMNAMAPK1CES2CES1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1683895-B1 | LIQUID COOLANT COMPOSITION | SHISHIAI KK (JP) | 2018-08-08 | — | — | EP | disclosed |
| EP-2554621-A1 | COOLING LIQUID COMPOSITION | Shishiai-Kabushikigaisha (JP) | 2013-02-06 | — | — | EP | disclosed |
| US-20130020530-A1 | LIQUID COOLING COMPOSITION | SHISHIAI-KABUSHIKIGAISHA (JP) | 2013-01-24 | — | — | US | disclosed |
| EP-2003182-A9 | COOLANT COMPOSITION | Shishiai-Kabushikigaisha (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-20090045376-A1 | Coolant Composition | SHISHIAI-KABUSHIKIGAISHA (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-2003182-A2 | COOLANT COMPOSITION | Shishiai-Kabushikigaisha (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-7258814-B2 | Excellent corrosion preventing properties for aluminum and aluminum alloys at high temperatures containing a glycol; a monobasic aromatic carboxylic acid; a Ca, Sr or Mg compound; and 2-phosphonobutane-1,2,4-tricarboxylic acid or a salt as a corrosion inhibitor | SHISHIAI-KABUSHIKIGAISHA (JP) | 2007-08-21 | — | — | US | disclosed |
| US-20070096054-A1 | Coolant composition and methods of use thereof | SHISHIAI-KABUSHIKIGAISHA (JP) | 2007-05-03 | — | — | US | disclosed |
| US-20060273283-A1 | Coolant composition | SHISHIAI-KABUSHIKIGAISHA (JP) | 2006-12-07 | — | — | US | disclosed |
| US-20060237685-A1 | Coolant composition and methods of use thereof | SHISHIAI-KABUSHIKIGAISHA (JP) | 2006-10-26 | — | — | US | disclosed |
| EP-1688472-A1 | COOLING FLUID COMPOSITION | Shishiai-Kabushikigaisha (JP) | 2006-08-09 | — | — | EP | disclosed |
| EP-1683895-A1 | LIQUID COOLANT COMPOSITION | Shishiai-Kabushikigaisha (JP) | 2006-07-26 | — | — | EP | disclosed |
| EP-1081250-B1 | Low phosphorus coolant composition | CCI KABUSHIKI KAISHA (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-6508951-B1 | Low Phosphorus content, heat exchange systems for internal combustion engines; aliphatic dibasic acids, alkyl benzoic acids, strontium compounds, phosphoric acids and alkali metal phosphates; glycol; triazole or thiazole corrosion inhibitors | CCI KABUSHIKI KAISHA (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-1081250-A1 | Low phosphorus coolant composition | CCI Kabushiki Kaisha (JP) | 2001-03-07 | — | — | EP | disclosed |