Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932177 | 0.86 | HSD11B1 (0.75) | HSD11B1ROCK2 | |
| SCHEMBL1854173 | 0.86 | HSD11B1 (0.76) | HSD11B1ROCK2 | |
| SCHEMBL3938067 | 0.83 | HSD11B1 (0.71) | HSD11B1 | |
| SCHEMBL1855894 | 0.82 | HSD11B1 (1.00) | HSD11B1ROCK2 | |
| SCHEMBL4171896 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3929905 | 0.79 | HSD11B1 (0.67) | HSD11B1ROCK2 | |
| SCHEMBL3929966 | 0.79 | HSD11B1 (1.00) | HSD11B1ROCK2 | |
| SCHEMBL1857917 | 0.78 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3940195 | 0.76 | HSD11B1 (0.78) | HSD11B1ROCK2 | |
| SCHEMBL28780902 | 0.74 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044057-A2 | DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | Sanofi-Aventis (FR) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008000950-A2 | DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | SANOFI-AVENTIS (FR) | 2008-01-03 | — | — | WO | disclosed |