Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780902 | 0.95 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL1856847 | 0.83 | HSD11B1 (0.71) | HSD11B1POLB | |
| SCHEMBL1856848 | 0.83 | HSD11B1 (0.71) | HSD11B1POLB | |
| SCHEMBL1855894 | 0.83 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3929966 | 0.82 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL1857917 | 0.81 | HSD11B1 (1.00) | HSD11B1POLB | |
| SCHEMBL1860343 | 0.81 | HSD11B1 (0.68) | HSD11B1POLB | |
| SCHEMBL1857680 | 0.80 | HSD11B1 (0.67) | HSD11B1POLB | |
| SCHEMBL3934266 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL1860999 | 0.80 | HSD11B1 (0.66) | HSD11B1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176775-A1 | DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | SANOFI-AVENTIS (FR) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176775-A1 | DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | HSD11B1, HSD3B1, ADH1C | HSD11B1 1/4885POLB 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.