Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054789 | 0.70 | EGFR (0.37) | EGFR | |
| SCHEMBL3934464 | 0.70 | EGFR (0.38) | EGFR | |
| SCHEMBL3906666 | 0.67 | KDM4E (0.39) | — | |
| SCHEMBL3941587 | 0.67 | EGFR (0.34) | EGFR | |
| SCHEMBL3942850 | 0.65 | — | — | |
| SCHEMBL6119198 | 0.64 | EGFR (0.50) | EGFRPIK3CDPIK3CA | |
| SCHEMBL29865299 | 0.64 | EGFR (0.50) | EGFRPIK3CDPIK3CA | |
| SCHEMBL2393986 | 0.62 | — | — | |
| SCHEMBL8311252 | 0.61 | EGFR (0.38) | EGFR | |
| SCHEMBL20483 | 0.61 | EGFR (0.47) | EGFRPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010156-A2 | SUBSTITUTED PHENYLPROPOARGYL COMPOUNDS, METHODS FOR THE PRODUCTION THEREOF, AND USE OF SAME AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-01-22 | — | — | WO | disclosed |
| EP-2017264-A1 | Substituted phenyl propargyl compounds, method for their manufacture and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2009-01-21 | — | — | EP | disclosed |