Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 12/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945562 | 0.89 | CHRM4 (0.59) | CHRM4ACHECHRM2CHRM1CHRM5 | |
| SCHEMBL3589414 | 0.89 | KMT2A (0.53) | CHRM4ACHEMAOAMAOBBCHE | |
| SCHEMBL2981417 | 0.83 | ACHE (0.48) | CHRM4ACHEMAOAMAOBCHRM2 | |
| SCHEMBL3941799 | 0.82 | CHRM4 (0.53) | CHRM4ACHEMAOAMAOBCHRM2 | |
| SCHEMBL3939238 | 0.80 | CHRM4 (0.53) | CHRM4ACHEMAOAMAOBCHRM2 | |
| SCHEMBL3592322 | 0.78 | POLB (0.50) | CHRM4ACHEBCHEALDH1A1 | |
| SCHEMBL344551 | 0.78 | CHRM4 (0.60) | CHRM4CHRM2 | |
| SCHEMBL3589417 | 0.76 | ALDH1A1 (0.52) | ACHEBCHEALDH1A1TDP1 | |
| SCHEMBL3937456 | 0.76 | CHRM4 (0.68) | CHRM4ACHE | |
| SCHEMBL3937038 | 0.75 | CHRM4 (0.52) | CHRM4ACHEMAOAMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |