Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 10/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941799 | 0.91 | CHRM4 (0.53) | CHRM4ACHEBCHECHRM2 | |
| SCHEMBL3592322 | 0.89 | POLB (0.50) | CHRM4ACHEBCHE | |
| SCHEMBL3935459 | 0.89 | CHRM4 (0.59) | CHRM4ACHEBCHECHRM2CHRM1 | |
| SCHEMBL3939238 | 0.85 | CHRM4 (0.53) | CHRM4ACHEBCHECHRM2 | |
| SCHEMBL3937038 | 0.85 | CHRM4 (0.52) | CHRM4ACHEBCHE | |
| SCHEMBL2974797 | 0.83 | CHRM4 (0.49) | CHRM4ACHEBCHECHRM2CHRM1 | |
| SCHEMBL3946467 | 0.78 | ACHE (0.52) | CHRM4ACHECHRM2 | |
| SCHEMBL3589414 | 0.78 | KMT2A (0.53) | CHRM4ACHEBCHE | |
| SCHEMBL3937725 | 0.78 | MAOA (0.52) | CHRM4ACHEBCHE | |
| SCHEMBL3592324 | 0.77 | ACHE (0.47) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |