Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | F2R | P25116 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935539 | 0.88 | MAPK1 (0.59) | ALDH1A1SMN1; SMN2LMNAL3MBTL1MAPT | |
| SCHEMBL3945213 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAL3MBTL1MAPT | |
| SCHEMBL2908215 | 0.81 | F2R (0.74) | ALDH1A1LMNAL3MBTL1MAPTKMT2A | |
| SCHEMBL3934665 | 0.81 | KMT2A (0.47) | ALDH1A1SMN1; SMN2LMNAL3MBTL1MAPT | |
| SCHEMBL3938938 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAL3MBTL1MAPTKMT2A | |
| SCHEMBL1399140 | 0.81 | F2R (0.64) | ALDH1A1SMN1; SMN2LMNAL3MBTL1MAPT | |
| SCHEMBL1399142 | 0.81 | F2R (0.64) | ALDH1A1SMN1; SMN2LMNAL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL8821987 | 0.79 | SIGMAR1 (0.53) | ALDH1A1KMT2AMAPK1KDM4EMEN1 | |
| SCHEMBL3939614 | 0.78 | CYP1A2 (0.49) | ALDH1A1SMN1; SMN2LMNAL3MBTL1KMT2A | |
| SCHEMBL3932252 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046748-A1 | PHENYLPENTADIENOYL DERIVATIVES AND THEIR USE AS PAR 1 ANTAGONISTS | Pierre Fabre Medicament (FR) | 2009-04-15 | — | — | EP | claimed |
| WO-2007147822-A1 | PHENYLPENTADIENOYL DERIVATIVES AND THEIR USE AS PAR 1 ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 2007-12-27 | — | — | WO | claimed |