Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937178 | 0.85 | NFE2L2 (0.46) | KMT2AALDH1A1CYP2C19CYP3A4MAPT | |
| SCHEMBL3938938 | 0.83 | ALDH1A1 (0.54) | KMT2AALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL3937145 | 0.82 | L3MBTL1 (0.41) | KMT2AALDH1A1LMNACYP2D6CYP2C9 | |
| SCHEMBL3935485 | 0.81 | ALDH1A1 (0.54) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3939614 | 0.80 | CYP1A2 (0.49) | KMT2AALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL1399046 | 0.80 | KMT2A (0.62) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL1399044 | 0.80 | KMT2A (0.62) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3932252 | 0.80 | ALDH1A1 (0.49) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3935539 | 0.79 | MAPK1 (0.59) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3945213 | 0.78 | ALDH1A1 (0.54) | KMT2AALDH1A1LMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046748-A1 | PHENYLPENTADIENOYL DERIVATIVES AND THEIR USE AS PAR 1 ANTAGONISTS | Pierre Fabre Medicament (FR) | 2009-04-15 | — | — | EP | claimed |
| WO-2007147822-A1 | PHENYLPENTADIENOYL DERIVATIVES AND THEIR USE AS PAR 1 ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 2007-12-27 | — | — | WO | claimed |