Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924887 | 0.89 | AGBL2 (0.55) | L3MBTL1HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL3930089 | 0.86 | L3MBTL1 (0.48) | L3MBTL1HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL3925047 | 0.85 | L3MBTL1 (0.47) | L3MBTL1HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL4376390 | 0.85 | L3MBTL1 (0.64) | L3MBTL1HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL3929580 | 0.84 | L3MBTL1 (0.46) | L3MBTL1HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL3932258 | 0.82 | MAPT (0.56) | L3MBTL1HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL3929230 | 0.81 | L3MBTL1 (0.44) | L3MBTL1HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL3926909 | 0.81 | MAPK1 (0.44) | L3MBTL1HPGDMAPTALDH1A1KMT2A | |
| SCHEMBL3926414 | 0.79 | TDP1 (0.52) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL1855724 | 0.78 | MAPT (0.60) | L3MBTL1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |