Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azelaic Acid SCHEMBL27562613 | 0.92 | MAPT (0.57) | MAPTGAAALDH1A1KMT2AGLA | |
| SCHEMBL5717719 | 0.91 | MAPT (0.58) | MAPTGAAALDH1A1KMT2AGLA | |
| SCHEMBL27562611 | 0.85 | GAA (0.54) | MAPTGAAALDH1A1KMT2AGLA | |
| SCHEMBL3936887 | 0.84 | AGBL2 (0.52) | MAPTGAAALDH1A1KMT2AGLA | |
| SCHEMBL3928210 | 0.84 | AGBL2 (0.68) | MAPTGAAALDH1A1KMT2AGLA | |
| SCHEMBL27716277 | 0.82 | AGBL2 (0.69) | MAPTALDH1A1KMT2AGLAAGBL2 | |
| SCHEMBL3935804 | 0.82 | L3MBTL1 (0.59) | MAPTGAAALDH1A1KMT2AAGBL2 | |
| SCHEMBL3926612 | 0.81 | MAPT (0.60) | MAPTALDH1A1KMT2AGLAAGBL2 | |
| SCHEMBL1855724 | 0.81 | MAPT (0.60) | MAPTALDH1A1KMT2AGLAAGBL2 | |
| SCHEMBL5204893 | 0.81 | MAPT (0.57) | MAPTGAAALDH1A1KMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |