Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942328 | 0.86 | — | — | |
| Beta-Alanine SCHEMBL14742051 | 0.72 | LMNA (0.55) | LMNATHRBBLMKMT2ANPSR1 | |
| Beta-Alanine SCHEMBL11287803 | 0.72 | — | — | |
| SCHEMBL11123306 | 0.71 | ALOX15 (0.31) | TSHRALOX15 | |
| SCHEMBL393856 | 0.71 | — | — | |
| Beta-Alanine SCHEMBL8102166 | 0.70 | LMNA (0.58) | LMNATHRBBLMKMT2ANPSR1 | |
| Beta-Alanine SCHEMBL15021967 | 0.70 | LMNA (0.58) | LMNATHRBBLMKMT2ANPSR1 | |
| Beta-Alanine SCHEMBL20411566 | 0.69 | — | — | |
| Beta-Alanine SCHEMBL18281085 | 0.69 | — | — | |
| Beta-Alanine SCHEMBL21500 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8100978-B2 | Prosthetic intervertebral discs having expandable cores that are implantable using minimally invasive surgical techniques | SPINAL KINETICS INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110144754-A1 | Prosthetic intervertebral discs assemblies having compressible core elements with enhanced torque transmission | SPINAL KINETICS LLC | 2011-06-16 | — | — | US | disclosed |
| US-20110115110-A1 | Method of Making Silicone Hydrogels with Fluorinated Side Chain Polysiloxanes | KUNZLER JAY F | 2011-05-19 | — | — | US | disclosed |
| US-20110082552-A1 | Prosthetic Intervertebral Discs Implantable By Minimally Invasive Surgical Techniques | SPINAL KINETICS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-7887592-B2 | Prosthetic intervertebral discs assemblies having compressible core elements with enhanced torque transmission | SPINAL KINETICS, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| US-7875687-B2 | copolymerized with hydrophilic n-vinylpyrrolidinone monomer; high oxygen permeability contact lenses; biocompatability | BAUSCH & LOMB INCORPORATED (US) | 2011-01-25 | — | — | US | disclosed |