SCHEMBL3935982

SCHEMBL3935982

C=CC(CCCCCCCCCCCCCCCC)C(=O)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ZDHHC2 Q9UIJ5 1/20 0.47
FAAH O00519 6/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
THRB P10828 2/20 0.43
ALDH1A1 P00352 2/20 0.42
THRA P10827 1/20 0.42
CNR2 P34972 1/20 0.42
TSHR P16473 1/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL766470 0.82 ATM (0.45) ZDHHC2FAAHTHRBALDH1A1TSHR
SCHEMBL29163411 0.81 ZDHHC2 (0.49) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL11296486 0.81 ZDHHC2 (0.49) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL3929624 0.81 ZDHHC2 (0.49) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL7732099 0.81 TDP1 (0.55) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL7734011 0.81 TDP1 (0.55) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL7112547 0.80 GPR84 (0.51) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL11699133 0.80 PRSS1 (0.50) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL7857923 0.80 TDP1 (0.50) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL1900961 0.80 PRSS1 (0.50) ZDHHC2FAAHPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481157-B2 Melt extruded fibers and methods of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-09 US disclosed
EP-2038457-A1 PARTICULATE-LOADED POLYMER FIBERS AND EXTRUSION METHODS 3M Innovative Properties Company (US) 2009-03-25 EP disclosed
US-7476352-B2 Lubricated flow fiber extrusion 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-01-13 US disclosed
US-20080003430-A1 PARTICULATE-LOADED POLYMER FIBERS AND EXTRUSION METHODS 3M INNOVATIVE PROPERTIES COMPANY 2008-01-03 US disclosed
WO-2008002724-A1 PARTICULATE-LOADED POLYMER FIBERS AND EXTRUSION METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-01-03 WO disclosed
US-20070154708-A1 MELT EXTRUDED FIBERS AND METHODS OF MAKING THE SAME 3M INOVATIVE PROPERTIES COMPANY 2007-07-05 US disclosed
EP-1753898-A1 LUBRICATED FLOW FIBER EXTRUSION 3M Innovative Properties Company (US) 2007-02-21 EP disclosed
WO-2005116308-A1 LUBRICATED FLOW FIBER EXTRUSION 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-12-08 WO disclosed
US-20050258562-A1 Lubricated flow fiber extrusion 3M INNOVATIVE PROPERTIES COMPANY 2005-11-24 US disclosed
US-4519909-A HOMOGENEOUS, THREE-DIMENSIONAL POLYMER STRUCTURE AKZONA INCORPORATED (US) 1985-05-28 US disclosed
US-4247498-A THERMOPLASTICS AKZONA INCORPORATED (US) 1981-01-27 US disclosed