SCHEMBL3936005

SCHEMBL3936005

O=[C]OC(O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
MAPK1 P28482 1/20 0.43
TSHR P16473 1/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2C P18825 1/20 0.40
HIF1A Q16665 1/20 0.40
CYP2D6 P10635 2/20 0.39
SRC P12931 1/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
CYP1A2 P05177 1/20 0.38
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL857 0.76 IDO1 (0.39) LMNAMAPK1TSHRADRA2ACYP2D6
SCHEMBL710572 0.74 CYP2D6 (0.46) LMNAMAPK1ALDH1A1KDM4EL3MBTL1
SCHEMBL16970628 0.73 HCAR2 (0.43) LMNAALDH1A1KDM4EADRA2AADRA2C
SCHEMBL16970750 0.73 HCAR2 (0.43) LMNAALDH1A1KDM4EADRA2AADRA2C
SCHEMBL119992 0.73 TSHR (0.44) LMNAMAPK1TSHRALDH1A1CYP2D6
SCHEMBL7454768 0.73 TSHR (0.44) LMNAMAPK1TSHRALDH1A1CYP2D6
SCHEMBL96935 0.73 HCAR2 (0.43) LMNAALDH1A1KDM4EADRA2AADRA2C
SCHEMBL2657967 0.73 CYP2D6 (0.34) LMNAMAPK1TSHRALDH1A1CYP2D6
SCHEMBL535087 0.73 DPP4 (0.44) LMNAALDH1A1KDM4EADRA2AADRA2C
SCHEMBL131810 0.73 CES2 (0.41) LMNAMAPK1TSHRALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018134412-A1 ANTIMICROBIAL COMPOUNDS AND USES THEREOF BIOSYNTH AG (CH) 2018-07-26 WO claimed
US-20200289662-A1 ANTIBODY-ACTIVE AGENT CONJUGATES AND METHODS OF USE LEGOCHEM BIOSCIENCES, INC. (KR) 2020-09-17 US disclosed
US-10583197-B2 Antibody-active agent conjugates and methods of use LEGOCHEM BIOSCIENCES, INC. (KR) 2020-03-10 US disclosed
EP-3610889-A1 PROTEIN-ACTIVE AGENT CONJUGATES AND METHOD FOR PREPARING THE SAME LegoChem Biosciences, Inc. (KR) 2020-02-19 EP disclosed
EP-2707031-B1 PROTEIN-ACTIVE AGENT CONJUGATES AND METHOD FOR PREPARING THE SAME LEGOCHEM BIOSCIENCES INC (KR) 2019-06-26 EP disclosed
WO-2018134412-A1 ANTIMICROBIAL COMPOUNDS AND USES THEREOF BIOSYNTH AG (CH) 2018-07-26 WO disclosed
US-20180021451-A1 ANTIBODY-ACTIVE AGENT CONJUGATES AND METHODS OF USE LIGACHEM BIOSCIENCES INC. (KR) 2018-01-25 US disclosed
US-9669107-B2 Antibody-active agent conjugates and methods of use LEGOCHEM BIOSCIENCES, INC. (KR) 2017-06-06 US disclosed
US-20160213786-A1 PROTEIN-ACTIVE AGENT CONJUGATES AND METHODS OF USE LEGOCHEM BIOSCIENCES, INC. (KR) 2016-07-28 US disclosed
US-20150105541-A1 ANTIBODY-ACTIVE AGENT CONJUGATES AND METHODS OF USE LIGACHEM BIOSCIENCES INC. (KR) 2015-04-16 US disclosed
EP-1484191-A1 REWRITABLE OPTICAL INFORMATION RECORDING MEDIUM AND RECORDING/REPRODUCING METHOD, RECORDING/REPRODUCING DEVICE Sony Corporation (JP) 2004-12-08 EP disclosed
US-20030194646-A1 Mono-, di-, and triazaporphyrin compounds optionally in the form of a metal or metalloid complex MITSUI CHEMICALS, INC. (JP) 2003-10-16 US disclosed
US-6627288-B1 Optical recording medium and porphycene compound MITSUI CHEMICALS, INC. (JP) 2003-09-30 US disclosed
US-20030091931-A1 Benzbisazole compound and optical recording medium containing the compound MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
EP-1262966-A2 Optical recording medium and novel azaporphyrin compound Mitsui Chemicals, Inc. (JP) 2002-12-04 EP disclosed
EP-1247655-A1 OPTICAL RECORDING MEDIUM AND NOVEL AZAPORPHYRIN COMPOUNDS Mitsui Chemicals, Inc. (JP) 2002-10-09 EP disclosed
EP-1245571-A1 BENZBISAZOLE COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE COMPOUND Mitsui Chemicals, Inc. (JP) 2002-10-02 EP disclosed
EP-1180765-A1 Optical recording medium and porphycene compound Mitsui Chemicals, Inc. (JP) 2002-02-20 EP disclosed
EP-0543662-B1 Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses SANKYO CO (JP) 1996-09-18 EP disclosed
EP-0543662-A2 Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1993-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160213786-A1 PROTEIN-ACTIVE AGENT CONJUGATES AND METHODS OF USE FNTA, FCGRT, GGT1 LMNA 2831/4885MAPK1 4198/4885TSHR 3900/4885
US-20150105541-A1 ANTIBODY-ACTIVE AGENT CONJUGATES AND METHODS OF USE FCGRT, CD47, FNTA LMNA 3728/4885MAPK1 4402/4885TSHR 3065/4885
US-20200289662-A1 ANTIBODY-ACTIVE AGENT CONJUGATES AND METHODS OF USE FCGRT, CD47, FNTA LMNA 3728/4885MAPK1 4402/4885TSHR 3065/4885
US-10583197-B2 Antibody-active agent conjugates and methods of use FNTA, FCGRT, CD47 LMNA 3858/4885MAPK1 4365/4885TSHR 3204/4885
US-20030091931-A1 Benzbisazole compound and optical recording medium containing the compound DAO, CACNA1I, KCNB2 LMNA 816/4885MAPK1 711/4885TSHR 3514/4885
US-20180021451-A1 ANTIBODY-ACTIVE AGENT CONJUGATES AND METHODS OF USE FCGRT, CD47, FNTA LMNA 3728/4885MAPK1 4402/4885TSHR 3065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.