Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770134 | 0.92 | POLB (0.52) | POLBGAASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL3933040 | 0.82 | FAAH (0.43) | POLBSMN1; SMN2MAPTNPC1KMT2A | |
| SCHEMBL17028594 | 0.81 | CYSLTR2 (0.45) | GAASMN1; SMN2HPGDKDM4EKMT2A | |
| SCHEMBL3925637 | 0.80 | KMT2A (0.49) | GAASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL3931150 | 0.80 | NPSR1 (0.44) | POLBSMN1; SMN2HPGDL3MBTL1MAPT | |
| SCHEMBL13962535 | 0.80 | CYP4F2 (0.43) | GAASMN1; SMN2CYP4F2CYP4A11CYSLTR2 | |
| SCHEMBL17967042 | 0.79 | CYSLTR2 (0.41) | GAASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL3924887 | 0.79 | AGBL2 (0.55) | POLBGAASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL3928855 | 0.78 | CYSLTR2 (0.46) | GAASMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL3930089 | 0.77 | L3MBTL1 (0.48) | POLBGAASMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |