Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.39 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL18155003 | 0.87 | KDM4E (0.43) | KDM4EGPR3ELANEDYRK1ADYRK1B | |
| SCHEMBL455351 | 0.85 | KDM4E (0.53) | KDM4EGPR3HTR6ALOX15 | |
| SCHEMBL27673186 | 0.83 | KDM4E (0.52) | KDM4EGPR3HTR6ALOX15 | |
| Iodide SCHEMBL4717590 | 0.83 | KDM4E (0.52) | KDM4EGPR3HTR6ALOX15 | |
| Hydrochloric Acid SCHEMBL3881151 | 0.83 | KDM4E (0.52) | KDM4EGPR3HTR6ALOX15 | |
| Formic Acid SCHEMBL3882912 | 0.82 | KDM4E (0.44) | KDM4EGPR3HTR6ALOX15 | |
| Hydrochloric Acid SCHEMBL27669383 | 0.82 | KDM4E (0.50) | KDM4EGPR3HTR6ALOX15 | |
| Hydrochloric Acid SCHEMBL28761791 | 0.82 | KDM4E (0.50) | KDM4EGPR3HTR6ALOX15 | |
| Trifluoroacetic Acid SCHEMBL4761165 | 0.80 | L3MBTL1 (0.50) | KDM4ETLR7ALDH1A1HPGDHSD17B10 | |
| SCHEMBL574757 | 0.80 | KDM4E (0.42) | KDM4EGPR3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086542-A1 | TOPICAL FORMULATIONS | Helperby Therapeutics Limited (GB) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008056151-A1 | TOPICAL FORMULATIONS | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-05-15 | — | — | WO | disclosed |