Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939254 | 0.90 | CHRM4 (0.57) | ACHE | |
| SCHEMBL4034063 | 0.85 | MEN1 (0.66) | MEN1KMT2ASIGMAR1KDM4EALDH1A1 | |
| SCHEMBL3946020 | 0.84 | ACHE (0.62) | ACHE | |
| SCHEMBL3937719 | 0.84 | ACHE (0.58) | ACHE | |
| SCHEMBL3937456 | 0.82 | CHRM4 (0.68) | ACHE | |
| SCHEMBL3946379 | 0.82 | MCHR1 (0.63) | ACHESIGMAR1 | |
| SCHEMBL3937725 | 0.82 | MAOA (0.52) | MEN1KMT2AACHE | |
| SCHEMBL3937764 | 0.82 | CHRM4 (0.57) | ACHE | |
| SCHEMBL3944672 | 0.81 | CHRM4 (0.71) | ACHESIGMAR1 | |
| SCHEMBL2967121 | 0.81 | KDM4E (0.52) | MEN1KMT2AACHESIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |