Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 0.47 |
| ▸ | PGR | P06401 | 6/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940208 | 0.86 | NR3C1 (0.48) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL3931094 | 0.84 | HIF1A (0.64) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL3938527 | 0.80 | HIF1A (0.71) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL3938530 | 0.80 | HIF1A (0.71) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL3930867 | 0.79 | PGR (0.44) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL10707185 | 0.78 | NR3C1 (0.46) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL10703308 | 0.76 | AR (0.54) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL11799696 | 0.75 | CYP3A4 (0.60) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL10705465 | 0.75 | CYP3A4 (0.60) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL10707423 | 0.74 | NR3C1 (0.59) | NR3C2PGRARCHRM1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976997-B1 | PROCESS FOR THE PREPARATION OF 11BETA-HYDR0XY-9BETA,10ALPHA-STEROIDS EMPLOYING AMYCOLATOPSIS MEDITERRANEI CELLS | SOLVAY PHARM GMBH (DE) | 2009-04-08 | — | — | EP | claimed |
| US-20070212751-A1 | Microbial method for the 11beta hydroxylation of 9beta, 10alpha-steriods | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-09-13 | — | — | US | claimed |
| EP-1976997-B1 | PROCESS FOR THE PREPARATION OF 11BETA-HYDR0XY-9BETA,10ALPHA-STEROIDS EMPLOYING AMYCOLATOPSIS MEDITERRANEI CELLS | SOLVAY PHARM GMBH (DE) | 2009-04-08 | — | — | EP | disclosed |
| US-20070212751-A1 | Microbial method for the 11beta hydroxylation of 9beta, 10alpha-steriods | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-09-13 | — | — | US | disclosed |