Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.37 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944884 | 0.86 | SPHK1 (0.45) | SPHK1SPHK2PLK1TRPV1 | |
| SCHEMBL977801 | 0.73 | SPHK1 (0.46) | SPHK1SPHK2FAAHPLK1PLK3 | |
| SCHEMBL979060 | 0.73 | SPHK1 (0.46) | SPHK1SPHK2FAAHPLK1PLK3 | |
| SCHEMBL25286795 | 0.72 | FAAH (0.62) | FAAH | |
| SCHEMBL982488 | 0.72 | EPHX2 (0.44) | SPHK1FAAH | |
| SCHEMBL981069 | 0.70 | FAAH (0.39) | FAAH | |
| SCHEMBL980153 | 0.70 | FAAH (0.39) | SPHK1FAAH | |
| SCHEMBL3946349 | 0.70 | FAAH (0.38) | FAAH | |
| SCHEMBL981221 | 0.70 | SPHK1 (0.51) | SPHK1SPHK2PLK1PLK3 | |
| SCHEMBL3941311 | 0.69 | S1PR1 (0.42) | SPHK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015485-A1 | CYCLIC INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2009-02-05 | — | — | WO | disclosed |