Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937357 | 0.86 | SPHK1 (0.42) | SPHK1SPHK2TRPV1PLK1 | |
| SCHEMBL981221 | 0.83 | SPHK1 (0.51) | SPHK1SPHK2PLK1 | |
| SCHEMBL980299 | 0.74 | EPHX2 (0.44) | SPHK1 | |
| SCHEMBL980126 | 0.72 | AKT1 (0.46) | — | |
| SCHEMBL979605 | 0.71 | SPHK1 (0.50) | SPHK1SPHK2PLK1 | |
| SCHEMBL13953019 | 0.70 | HAO1 (0.65) | — | |
| SCHEMBL11982117 | 0.69 | MAPT (0.60) | TRPV1PLK1 | |
| SCHEMBL28562555 | 0.69 | THRA (0.64) | TRPV1PLK1 | |
| SCHEMBL3796237 | 0.69 | THRA (0.59) | — | |
| SCHEMBL12040863 | 0.69 | THRA (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015485-A1 | CYCLIC INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2009-02-05 | — | — | WO | disclosed |