Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928450 | 0.93 | FAAH (0.56) | FAAH | |
| SCHEMBL3929765 | 0.88 | NPSR1 (0.46) | FAAH | |
| SCHEMBL14367471 | 0.82 | NPSR1 (0.43) | — | |
| SCHEMBL3931021 | 0.81 | FAAH (0.62) | FAAH | |
| SCHEMBL3929761 | 0.81 | NPSR1 (0.47) | — | |
| Piperazine SCHEMBL27767250 | 0.81 | NPSR1 (0.46) | — | |
| SCHEMBL3929988 | 0.77 | KDM4E (0.50) | — | |
| SCHEMBL3927527 | 0.76 | FAAH (0.55) | FAAH | |
| SCHEMBL3930008 | 0.76 | FAAH (0.64) | FAAH | |
| SCHEMBL3937875 | 0.73 | NPSR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044044-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |