Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929761 | 0.90 | NPSR1 (0.47) | NPSR1ALDH1A1PKMMAPTTSHR | |
| Piperazine SCHEMBL27767250 | 0.89 | NPSR1 (0.46) | NPSR1ALDH1A1PKMMAPTTSHR | |
| SCHEMBL3933704 | 0.86 | NPSR1 (0.47) | NPSR1ALDH1A1PKMMAPTTSHR | |
| SCHEMBL3928450 | 0.81 | FAAH (0.56) | — | |
| SCHEMBL3926126 | 0.80 | PTGDR2 (0.49) | ALDH1A1PKMMAPTHTTTHRB | |
| SCHEMBL3929765 | 0.78 | NPSR1 (0.46) | NPSR1ALDH1A1PKMMAPTTSHR | |
| SCHEMBL14367071 | 0.75 | ALDH1A1 (0.54) | ALDH1A1PKMMAPTTSHRHTT | |
| SCHEMBL4280876 | 0.75 | THRA (0.47) | NPSR1ALDH1A1HTTTHRATHRB | |
| SCHEMBL3933705 | 0.74 | THRA (0.43) | THRATHRBPTGDR2GAACXCR3 | |
| SCHEMBL3937822 | 0.73 | FAAH (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044044-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |