Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.30 |
| ▸ | CES1 | P23141 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737358 | 0.83 | AGBL2 (0.32) | AGBL2 | |
| SCHEMBL25991349 | 0.83 | GABRG2 (0.32) | AGBL2CES2CES1 | |
| SCHEMBL30318400 | 0.82 | AGBL2 (0.43) | APLNRAGBL2 | |
| SCHEMBL24123105 | 0.80 | IDH1 (0.39) | — | |
| SCHEMBL16224788 | 0.80 | S1PR3 (0.41) | — | |
| SCHEMBL34468435 | 0.80 | APLNR (0.32) | APLNRAGBL2 | |
| SCHEMBL30388688 | 0.80 | IDH1 (0.39) | — | |
| SCHEMBL588518 | 0.79 | PDE2A (0.32) | APLNRAGBL2 | |
| SCHEMBL588625 | 0.79 | PDE2A (0.32) | APLNRAGBL2 | |
| SCHEMBL22304409 | 0.79 | AGBL2 (0.30) | AGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119053588-A | P38 alpha-MK 2 inhibitor compound, pharmaceutical composition and application thereof | 长春金赛药业有限责任公司 | 2024-11-29 | — | — | CN | disclosed |
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |