SCHEMBL393880

SCHEMBL393880

Ic1ccc(-n2cccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
VHL P40337 1/20 0.50
ELOC Q15369 1/20 0.50
ELOB Q15370 1/20 0.50
GAA P10253 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
RAB9A P51151 4/20 0.46
ALDH1A1 P00352 4/20 0.46
NPC1 O15118 3/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
POLB P06746 3/20 0.43
NSD2 O96028 1/20 0.43
GRK2 P25098 1/20 0.43
CASP6 P55212 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44284 0.73 KDM4E (0.50) KDM4EVHLELOCELOBGAA
SCHEMBL636960 0.72 VHL (0.50) KDM4EVHLELOCELOBGAA
SCHEMBL2239811 0.72 ALDH1A1 (0.56) KDM4EVHLELOCELOBGAA
SCHEMBL196307 0.72 NOTUM (0.52) KDM4EVHLELOCELOBGAA
SCHEMBL11822364 0.72 KDM4E (0.50) KDM4EVHLELOCELOBGAA
SCHEMBL1260035 0.72 KDM4E (0.50) KDM4EVHLELOCELOBGAA
SCHEMBL1366622 0.72 L3MBTL1 (0.56) KDM4EVHLELOCELOBGAA
SCHEMBL16242550 0.72 VHL (0.61) KDM4EVHLELOCELOBGAA
SCHEMBL28553990 0.72 MAPT (0.56) KDM4EVHLELOCELOBGAA
SCHEMBL20319186 0.70 VHL (0.67) KDM4EVHLELOCELOBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112563571-A Additive for battery, secondary battery, battery module, battery pack and device 宁德时代新能源科技股份有限公司 2021-03-26 CN claimed
CN-105693588-A Fluorine-containing pyrrole diphenylacerylene organic solid fluorescent compound and synthetic method and application 华南师范大学 2016-06-22 CN claimed
CN-104418824-A 1-(4-iodophenyl)pyrrole and preparation method thereof TIANJIN HEOWNS BIOCHEMISTRY TECHNOLOGY CO LTD 2015-03-18 CN claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
US-12391781-B2 Black particles, black coating material, coating film, and black matrix for color filters SEKISUI CHEMICAL CO., LTD. (JP) 2025-08-19 US disclosed
EP-4063426-B1 BLACK PARTICLES, BLACK COATING MATERIAL, COATING FILM, AND BLACK MATRIX FOR COLOR FILTERS SEKISUI CHEMICAL CO LTD (JP) 2025-06-18 EP disclosed
CN-120004934-A Preparation method of benzo-silicon-containing octatomic ring compound 郑州大学 2025-05-16 CN disclosed
US-12291501-B2 N,N diethyl-N'phenylpiperazine alpha 7 and alpha 9 nicotinic acetylcholine receptor agonists and antagonists UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2025-05-06 US disclosed
US-20240092738-A1 N,N diethyl-N'phenylpiperazine alpha 7 and alpha 9 nicotinic acetylcholine receptor agonists and antagonists UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2024-03-21 US disclosed
CN-114502677-B Black particles, black paint, coating film, and black matrix for color filter 积水化学工业株式会社 2023-11-14 CN disclosed
US-20230095032-A1 N,N diethyl-N'phenylpiperazine alpha 7 and alpha 9 nicotinic acetylcholine receptor agonists and antagonists UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2023-03-30 US disclosed
EP-0929563-A1 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY Abbott Laboratories (US) 1999-07-21 EP disclosed
US-5917038-A REACTING PROPIOLAMIDE WITH ACTIVATED AROMATIC RING IN THE PRESENCE OF A PALLADIUM CATALYST ELI LILLY AND COMPANY (US) 1999-06-29 US disclosed
WO-1999018941-A2 Ih-MODULATORS AKZO NOBEL N.V. (NL) 1999-04-22 WO disclosed
WO-1999010331-A1 ARYLPYRIDAZINONES AS PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS ABBOTT LABORATORIES (US) 1999-03-04 WO disclosed
US-5866549-A MACROLIDE ANTIBIOTICS ABBOTT LABORATORIES (US) 1999-02-02 US disclosed
US-5856510-A SELECTIVE FOR 5-HT(1D)-LIKE RECEPTORS ALLELIX BIOPHARMACEUTICALS INC. (CA) 1999-01-05 US disclosed
WO-1998022429-A1 PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES ELI LILLY AND COMPANY (US) 1998-05-28 WO disclosed
WO-1998009978-A1 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY ABBOTT LABORATORIES (US) 1998-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12291501-B2 N,N diethyl-N'phenylpiperazine alpha 7 and alpha 9 nicotinic acetylcholine receptor agonists and antagonists CHRNA7, CHRNA9, CHRNE KDM4E 1926/4885VHL 4355/4885ELOC 2668/4885
US-20230095032-A1 N,N diethyl-N'phenylpiperazine alpha 7 and alpha 9 nicotinic acetylcholine receptor agonists and antagonists CHRNA7, CHRNA9, CHRNE KDM4E 1926/4885VHL 4355/4885ELOC 2668/4885
US-20240092738-A1 N,N diethyl-N'phenylpiperazine alpha 7 and alpha 9 nicotinic acetylcholine receptor agonists and antagonists CHRNA7, CHRNA9, CHRNE KDM4E 1926/4885VHL 4355/4885ELOC 2668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.