Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942242 | 0.94 | FAAH (0.77) | FAAHCYP3A4CYP2C19SMN1; SMN2NPSR1 | |
| SCHEMBL4017908 | 0.89 | FAAH (0.72) | FAAHRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL3941303 | 0.89 | FAAH (0.82) | FAAHALPLIGF1R | |
| SCHEMBL3929062 | 0.88 | FAAH (0.75) | FAAHSMN1; SMN2LMNAALPL | |
| SCHEMBL3941343 | 0.88 | FAAH (0.86) | FAAHSMN1; SMN2NPSR1LMNAGAA | |
| SCHEMBL3942978 | 0.87 | FAAH (0.86) | FAAHSMN1; SMN2LMNAGAATSHR | |
| SCHEMBL3931635 | 0.87 | FAAH (0.71) | FAAHRAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL3932388 | 0.87 | FAAH (0.77) | FAAHLMNAMEN1MAPTKMT2A | |
| SCHEMBL3932545 | 0.87 | FAAH (0.79) | FAAHMAPTAKR1C3ALPLIGF1R | |
| SCHEMBL3940445 | 0.87 | FAAH (0.84) | FAAHRAB9ASMN1; SMN2NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |