Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.72 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942242 | 0.91 | FAAH (0.77) | FAAHAKR1C3MAPTCYP3A4CYP2C19 | |
| SCHEMBL4015887 | 0.90 | FAAH (0.76) | FAAHAKR1C3MAPT | |
| SCHEMBL3939610 | 0.89 | FAAH (0.74) | FAAHAKR1C3MAPTCYP3A4CYP2C19 | |
| SCHEMBL4014297 | 0.89 | FAAH (0.76) | FAAHAKR1C3SMN1; SMN2 | |
| SCHEMBL4018971 | 0.89 | FAAH (0.76) | FAAHMAPTCYP3A4 | |
| SCHEMBL4018033 | 0.88 | FAAH (0.65) | FAAHAKR1C3PPARGPPARDPPARA | |
| SCHEMBL4010751 | 0.86 | FAAH (0.85) | FAAHAKR1C3 | |
| SCHEMBL3941303 | 0.86 | FAAH (0.82) | FAAH | |
| SCHEMBL3929062 | 0.85 | FAAH (0.75) | FAAHSMN1; SMN2 | |
| SCHEMBL3941343 | 0.85 | FAAH (0.86) | FAAHMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |