Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945339 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL3942488 | 0.85 | RAB9A (0.49) | GABRA1GABRB2RAB9ANPC1GABRG2 | |
| SCHEMBL4204118 | 0.80 | HDAC1 (0.35) | ALDH1A1MAPTL3MBTL1GABRA1GABRB2 | |
| SCHEMBL3950920 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MAPTL3MBTL1KDM4ETDP1 | |
| SCHEMBL4211551 | 0.78 | MAPT (0.59) | ALDH1A1MAPTL3MBTL1KDM4ETDP1 | |
| SCHEMBL3950434 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1KDM4ETDP1 | |
| SCHEMBL3941329 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1KDM4ENPC1 | |
| SCHEMBL4158477 | 0.77 | MAPT (0.60) | ALDH1A1MAPTL3MBTL1KDM4ETDP1 | |
| SCHEMBL3950369 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1KDM4ERAB9A | |
| SCHEMBL4199731 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |