Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944224 | 0.87 | DRD2 (0.48) | ALDH1A1MAPTL3MBTL1DRD2HTR2A | |
| SCHEMBL4199731 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1DRD2HTR2A | |
| SCHEMBL3939700 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1MAPK14HDAC1 | |
| SCHEMBL3942488 | 0.85 | RAB9A (0.49) | KMT2AHDAC1HDAC6NPC1RAB9A | |
| SCHEMBL3120950 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPTL3MBTL1DRD2HTR2A | |
| SCHEMBL4211551 | 0.78 | MAPT (0.59) | ALDH1A1MAPTL3MBTL1KMT2ANPC1 | |
| SCHEMBL4304078 | 0.78 | MAPK14 (0.43) | ALDH1A1MAPTL3MBTL1DRD2HTR2A | |
| SCHEMBL3950434 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1KMT2ANPC1 | |
| SCHEMBL3941329 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1KMT2ANPC1 | |
| SCHEMBL4158477 | 0.77 | MAPT (0.60) | ALDH1A1MAPTL3MBTL1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |