Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 4/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995668 | 1.00 | CLK1 (0.47) | CLK1DYRK1ACDK5CDK5R1CYP3A4 | |
| SCHEMBL7705046 | 0.79 | FGFR1 (0.49) | CLK1DYRK1ALMNAFGFR1DHFR | |
| SCHEMBL2916502 | 0.79 | FGFR1 (0.50) | CLK1DYRK1ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL1041168 | 0.79 | PLAU (0.55) | CLK1DYRK1ACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL23003121 | 0.79 | CLK1 (0.44) | CLK1DYRK1ACDK5CDK5R1PDPK1 | |
| SCHEMBL25450062 | 0.79 | BACE1 (0.55) | CLK1DYRK1ACDK5CDK5R1PDPK1 | |
| SCHEMBL25449349 | 0.79 | CLK1 (0.41) | CLK1DYRK1ACDK5CDK5R1FGFR1 | |
| SCHEMBL22136018 | 0.75 | CLK1 (0.62) | CLK1DYRK1ACDK5CDK5R1CYP3A4 | |
| SCHEMBL24615646 | 0.75 | P2RX3 (0.49) | CLK1DYRK1ACYP3A4LMNACYP1A2 | |
| SCHEMBL1039857 | 0.75 | MCHR1 (0.59) | CYP3A4ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602780-A | New compound and its pharmacologically acceptable salt | 明治制果药业株式会社 | 2018-09-28 | — | — | CN | claimed |
| CN-108602780-A | New compound and its pharmacologically acceptable salt | 明治制果药业株式会社 | 2018-09-28 | — | — | CN | disclosed |
| EP-2894157-B1 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG ELECTRONICS CO LTD (KR) | 2018-04-04 | — | — | EP | disclosed |
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| CN-101489989-A | Pentadiene amide derivative | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
| CN-101309586-A | Thiazole compounds as fungicides | BAYER CROPSCIENCE AG (DE) | 2008-11-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | CLK1 4240/4885DYRK1A 481/4885CDK5 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.