Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.76 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933531 | 0.92 | FAAH (0.78) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3932545 | 0.90 | FAAH (0.79) | FAAHALPLAKR1C3IGF1RMKNK1 | |
| SCHEMBL3934243 | 0.87 | FAAH (0.83) | FAAHAKR1C3ALDH1A1LMNAMAPK1 | |
| SCHEMBL3942978 | 0.87 | FAAH (0.86) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3941135 | 0.87 | FAAH (1.00) | FAAHAKR1C3ALDH1A1LMNAMAPK1 | |
| SCHEMBL3933101 | 0.86 | FAAH (0.73) | FAAHALPLAKR1C3IGF1RMKNK1 | |
| SCHEMBL3944150 | 0.86 | FAAH (0.70) | FAAHALPLIGF1R | |
| SCHEMBL3934738 | 0.85 | FAAH (0.72) | FAAHALPLAKR1C3ALDH1A1LMNA | |
| SCHEMBL3932908 | 0.85 | FAAH (0.83) | FAAHALPLAKR1C3ALDH1A1LMNA | |
| SCHEMBL3939389 | 0.85 | FAAH (0.83) | FAAHAKR1C3ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |