Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.73 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932545 | 0.95 | FAAH (0.79) | FAAHALPLMKNK1IGF1RAKR1C3 | |
| SCHEMBL3942417 | 0.94 | FAAH (0.78) | FAAHALPLMKNK1IGF1R | |
| SCHEMBL3941303 | 0.91 | FAAH (0.82) | FAAHALPLMKNK1IGF1R | |
| SCHEMBL3944150 | 0.90 | FAAH (0.70) | FAAHALPLIGF1R | |
| SCHEMBL3934738 | 0.90 | FAAH (0.72) | FAAHALPLMKNK1AKR1C3 | |
| SCHEMBL3931396 | 0.90 | FAAH (0.85) | FAAHMKNK1 | |
| SCHEMBL3943232 | 0.89 | FAAH (0.78) | FAAHMKNK1IGF1R | |
| SCHEMBL3939941 | 0.86 | FAAH (0.76) | FAAHALPLMKNK1IGF1RAKR1C3 | |
| SCHEMBL3932908 | 0.86 | FAAH (0.83) | FAAHALPLMKNK1AKR1C3 | |
| SCHEMBL3937394 | 0.85 | FAAH (0.75) | FAAHMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |