Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940471 | 1.00 | NPC1 (0.56) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL1405402 | 0.86 | NPC1 (0.65) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL1405403 | 0.86 | NPC1 (0.65) | NPC1RAB9ACASP3SENP8SENP7 | |
| Anisole SCHEMBL28873619 | 0.83 | NFE2L2 (0.60) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1405164 | 0.83 | GSK3B (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1405162 | 0.83 | GSK3B (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| Dinitrophenylene SCHEMBL27491213 | 0.81 | LMNA (0.63) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL30059246 | 0.81 | LMNA (0.61) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL515302 | 0.81 | LMNA (0.61) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL28218708 | 0.81 | LMNA (0.61) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7556844-B2 | Radiation curable photochromic inks | XEROX CORPORATION (US) | 2009-07-07 | — | — | US | disclosed |