SCHEMBL515302

SCHEMBL515302

COc1cccc([N+](=O)[O-])c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
TSHR P16473 2/20 0.61
NFE2L2 Q16236 2/20 0.61
MAPT P10636 5/20 0.57
ALDH1A1 P00352 4/20 0.57
CHRNB2 P17787 1/20 0.57
CHRNA4 P43681 1/20 0.57
ACHE P22303 1/20 0.57
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
MAPK1 P28482 1/20 0.55
HTT P42858 1/20 0.55
MAOB P27338 1/20 0.55
KEAP1 Q14145 1/20 0.55
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
POLB P06746 1/20 0.54
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28218708 1.00 LMNA (0.61) LMNATSHRNFE2L2MAPTALDH1A1
SCHEMBL30059246 1.00 LMNA (0.61) LMNATSHRNFE2L2MAPTALDH1A1
SCHEMBL28090002 0.98 NFE2L2 (0.59) LMNATSHRNFE2L2MAPTALDH1A1
SCHEMBL30612688 0.98 NFE2L2 (0.59) LMNATSHRNFE2L2MAPTALDH1A1
Methylamine SCHEMBL11814441 0.96 NFE2L2 (0.58) LMNATSHRNFE2L2MAPTALDH1A1
Nitrogen SCHEMBL8501917 0.96 NFE2L2 (0.58) LMNATSHRNFE2L2MAPTALDH1A1
Anisole SCHEMBL28873619 0.94 NFE2L2 (0.60) LMNATSHRNFE2L2MAPTALDH1A1
Nitrogen SCHEMBL8500176 0.94 NFE2L2 (0.56) LMNATSHRNFE2L2MAPTALDH1A1
SCHEMBL28255500 0.94 NFE2L2 (0.56) LMNATSHRNFE2L2MAPTALDH1A1
Cyanide SCHEMBL27784323 0.94 NFE2L2 (0.56) LMNATSHRNFE2L2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 766 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284758-B Intrinsic antibacterial nylon and preparation method and application thereof 桂林理工大学 2024-08-27 CN claimed
US-12037303-B2 Method for preparing diaryl p-phenylenediamine compounds SENNICS CO., LTD. (CN) 2024-07-16 US claimed
US-20240076264-A1 METHOD FOR PREPARING DIARYL P-PHENYLENEDIAMINE COMPOUNDS SENNICS CO., LTD. (CN) 2024-03-07 US claimed
WO-2024040766-A1 PREPARATION METHOD FOR DIARYL-P-PHENYLENEDIAMINE COMPOUND 圣奥化学科技有限公司 2024-02-29 WO claimed
CN-116897404-A Hybrid capacitor with improved ESR stability 基美电子公司 2023-10-17 CN claimed
CN-116199841-B Antibacterial agent and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-10-03 CN claimed
CN-116589361-A Preparation method of diaryl p-phenylenediamine compound 圣奥化学科技有限公司 2023-08-15 CN claimed
CN-116284758-A Intrinsic antibacterial nylon and preparation method and application thereof 桂林理工大学 2023-06-23 CN claimed
CN-116199841-A Antibacterial agent and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-06-02 CN claimed
CN-116135907-A Intrinsic antibacterial nylon and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-05-19 CN claimed
CN-1268936-A Method for producing compound contg. fluorine, in particular fluorobenzaldhydes and fluorobnzonitriles AVENTIS RES & TECHNOLOGY GMBH (DE) 2000-10-04 CN claimed
EP-1037873-A1 METHOD FOR PRODUCING ORGANIC HYDROXYLAMINES Consortium für elektrochemische Industrie GmbH (DE) 2000-09-27 EP claimed
EP-1015402-A1 METHOD FOR PRODUCING COMPOUNDS CONTAINING FLUORINE, IN PARTICULAR FLUOROBENZALDHYDES AND FLUOROBENZONITRILES Aventis Research & Technologies GmbH & Co. KG (DE) 2000-07-05 EP claimed
WO-2000012082-A1 FORMAMIDE COMPOUNDS AS THERAPEUTIC AGENTS GLAXO GROUP LIMITED (GB) 2000-03-09 WO claimed
WO-1999028289-A1 METHOD FOR PRODUCING ORGANIC HYDROXYLAMINES Consortium für elektrochemische Industrie GmbH (DE) 1999-06-10 WO claimed
WO-1999011588-A1 METHOD FOR PRODUCING COMPOUNDS CONTAINING FLUORINE, IN PARTICULAR FLUOROBENZALDHYDES AND FLUOROBENZONITRILES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-03-11 WO claimed
US-5744267-A COMPOSITE COMPRISING SECOND ORDER NONLINEAR OPTICAL DYE, POLYMERIC PHOTOCONDUCTOR, PHOTOSENSITIZER, PLASTICIZER ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF UNIVERSITY OF ARIZONA (US) 1998-04-28 US claimed
US-5037640-A Protective coating against ultraviolet radiation CLAIROL INCORPORATED (US) 1991-08-06 US claimed
CN-1003710-B New synthesis method of 4-nitro-benzene-beta-methoxyethyl ether 化学工业部沈阳化工研究院 1989-03-29 CN claimed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240076264-A1 METHOD FOR PREPARING DIARYL P-PHENYLENEDIAMINE COMPOUNDS C9, C1S, CCND2 LMNA 212/4885TSHR 4338/4885NFE2L2 359/4885
US-12037303-B2 Method for preparing diaryl p-phenylenediamine compounds C9, C1S, CCND2 LMNA 212/4885TSHR 4338/4885NFE2L2 359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.