Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931870 | 0.89 | PTGDR2 (0.49) | PTGDR2PKMTSHRKMT2AMAPT | |
| SCHEMBL3934209 | 0.87 | USP5 (0.47) | PTGDR2PKMTSHRKMT2AMAPT | |
| SCHEMBL3938376 | 0.84 | PTGDR2 (0.54) | PTGDR2PKMTSHRKMT2AMAPT | |
| SCHEMBL3932286 | 0.84 | MAPT (0.45) | PTGDR2PKMTSHRKMT2AMAPT | |
| SCHEMBL3942010 | 0.82 | USP5 (0.61) | PTGDR2PKMTSHRKMT2AUSP5 | |
| SCHEMBL3929084 | 0.81 | MAPT (0.55) | PTGDR2TSHRKMT2AMEN1MAPT | |
| SCHEMBL3941517 | 0.81 | MAPT (0.55) | PTGDR2TSHRKMT2AMEN1MAPT | |
| SCHEMBL3938045 | 0.81 | MAPT (0.55) | PTGDR2TSHRKMT2AMEN1MAPT | |
| SCHEMBL14366366 | 0.80 | PKM (0.49) | PKMTSHRKMT2AMEN1MAPT | |
| SCHEMBL3932377 | 0.77 | PKM (0.49) | PKMTSHRKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044017-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | claimed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | claimed |