Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP5 | P45974 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932377 | 0.90 | PKM (0.49) | PKMTSHRUSP5KMT2ALMNA | |
| SCHEMBL3931870 | 0.90 | PTGDR2 (0.49) | PKMTSHRUSP5KMT2APOLB | |
| SCHEMBL3941870 | 0.85 | PKM (0.55) | PKMTSHRUSP5KMT2ALMNA | |
| SCHEMBL3933582 | 0.83 | GAA (0.49) | PKMTSHRKMT2APOLBLMNA | |
| SCHEMBL3934209 | 0.81 | USP5 (0.47) | PKMTSHRUSP5KMT2AMAPT | |
| SCHEMBL3941103 | 0.80 | PTGDR2 (0.47) | PKMTSHRUSP5KMT2APOLB | |
| SCHEMBL3933560 | 0.79 | THRB (0.44) | PKMTSHRKMT2ALMNAMAPT | |
| SCHEMBL3932286 | 0.77 | MAPT (0.45) | PKMTSHRUSP5KMT2ALMNA | |
| SCHEMBL3933325 | 0.77 | KDM4E (0.47) | PKMTSHRKMT2ALMNAMAPT | |
| SCHEMBL3938376 | 0.77 | PTGDR2 (0.54) | PKMTSHRUSP5KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |