Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941130 | 1.00 | THRB (0.32) | THRBLMNATSHR | |
| SCHEMBL8664283 | 0.75 | GSR (0.31) | — | |
| SCHEMBL18568566 | 0.68 | — | — | |
| SCHEMBL9174554 | 0.67 | LMNA (0.39) | LMNATSHR | |
| Ethylene SCHEMBL27943894 | 0.64 | THRB (0.36) | THRB | |
| SCHEMBL14246980 | 0.62 | NOS3 (0.36) | THRB | |
| SCHEMBL19576613 | 0.62 | NOS3 (0.36) | THRB | |
| SCHEMBL5482041 | 0.62 | NOS3 (0.36) | THRB | |
| SCHEMBL7709398 | 0.62 | CYP19A1 (0.39) | THRBLMNATSHR | |
| SCHEMBL7706391 | 0.62 | CYP19A1 (0.39) | THRBLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009013293-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES USEFUL AS BACE INHIBITORS | NOVARTIS AG (CH) | 2009-01-29 | — | — | WO | disclosed |