Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3927189 | 0.79 | MAOB (0.50) | KCNH2MAPTRAB9ASMN1; SMN2MAOB | |
| SCHEMBL3939419 | 0.78 | CYP4F2 (0.54) | MAPTRAB9ASMN1; SMN2MAOBGAA | |
| SCHEMBL958531 | 0.78 | TSHR (0.50) | MAPTRAB9ANPC1SMN1; SMN2MAOB | |
| SCHEMBL9936997 | 0.76 | HPGDS (0.50) | KCNH2CYSLTR1 | |
| SCHEMBL9900670 | 0.73 | SMN1; SMN2 (0.45) | KCNH2MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9900672 | 0.73 | KCNH2 (0.44) | KCNH2MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL956156 | 0.73 | CDC7 (0.43) | RAB9ASMN1; SMN2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL4017016 | 0.72 | RAB9A (0.46) | KCNH2MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9905372 | 0.72 | XDH (0.59) | MAPTRAB9ANPC1SMN1; SMN2MAOB | |
| SCHEMBL5069229 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |