Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.37 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941742 | 1.00 | CTSL (0.43) | CTSLMAPTHCAR2CYP3A4CYP2C9 | |
| SCHEMBL3941734 | 1.00 | CTSL (0.43) | CTSLMAPTHCAR2CYP3A4CYP2C9 | |
| SCHEMBL122159 | 0.79 | CTSL (0.46) | CTSLMAPTHCAR2HTTMME | |
| SCHEMBL147688 | 0.79 | CTSL (0.46) | CTSLMAPTHCAR2HTTMME | |
| SCHEMBL2351295 | 0.78 | CTSL (0.47) | CTSLMAPTHCAR2CYP2C9CYP2C19 | |
| SCHEMBL14429286 | 0.76 | KMT2A (0.43) | CTSLMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15502196 | 0.75 | CTSL (0.41) | CTSLMAPTHCAR2CYP3A4CYP2C9 | |
| SCHEMBL23009196 | 0.75 | SLC1A1 (0.48) | CTSLMAPTHCAR2MAP3K7TAB1 | |
| SCHEMBL22793544 | 0.74 | CTSL (0.43) | CTSLMAPTCYP2C19HTTMME | |
| Hydrochloric Acid SCHEMBL29659070 | 0.74 | SLC1A1 (0.47) | CTSLMAPTHCAR2MAP3K7TAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009013293-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES USEFUL AS BACE INHIBITORS | NOVARTIS AG (CH) | 2009-01-29 | — | — | WO | disclosed |