Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942078 | 0.96 | PKM (0.46) | PKMRXFP1 | |
| SCHEMBL3949157 | 0.95 | RXFP1 (0.53) | PKMMEN1KMT2ARXFP1 | |
| SCHEMBL3951605 | 0.94 | RXFP1 (0.46) | MEN1KMT2ARXFP1 | |
| SCHEMBL3944657 | 0.94 | PKM (0.52) | PKMRXFP1 | |
| SCHEMBL3942026 | 0.93 | PKM (0.44) | PKMRXFP1 | |
| SCHEMBL3942701 | 0.93 | PKM (0.44) | PKMRXFP1 | |
| SCHEMBL3945458 | 0.93 | RXFP1 (0.51) | MEN1KMT2ARXFP1 | |
| SCHEMBL3951199 | 0.92 | RXFP1 (0.48) | RXFP1 | |
| SCHEMBL3943829 | 0.91 | RXFP1 (0.41) | PKMRXFP1 | |
| SCHEMBL3951915 | 0.90 | MMP1 (0.39) | PKMRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |