Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942078 | 0.95 | PKM (0.46) | PKMRXFP1L3MBTL1TP53 | |
| SCHEMBL3941702 | 0.94 | RXFP1 (0.47) | RXFP1 | |
| SCHEMBL3944657 | 0.93 | PKM (0.52) | PKMRXFP1L3MBTL1TP53 | |
| SCHEMBL3951605 | 0.93 | RXFP1 (0.46) | RXFP1 | |
| SCHEMBL3942352 | 0.93 | PKM (0.47) | PKMRXFP1 | |
| SCHEMBL3942026 | 0.93 | PKM (0.44) | PKMRXFP1L3MBTL1 | |
| SCHEMBL3945382 | 0.92 | TP53 (0.46) | PKML3MBTL1TP53 | |
| SCHEMBL3943534 | 0.92 | RXFP1 (0.40) | PKMRXFP1 | |
| SCHEMBL3949157 | 0.91 | RXFP1 (0.53) | PKMRXFP1 | |
| SCHEMBL3951199 | 0.91 | RXFP1 (0.48) | RXFP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |