Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | PLG | P00747 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.62 |
| ▸ | GABRP | O00591 | 1/20 | 0.62 |
| ▸ | GABRD | O14764 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL7530463 | 1.00 | NFKB1 (0.67) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL28031081 | 0.97 | NFKB1 (0.64) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL11873219 | 0.97 | NFKB1 (0.64) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL4681431 | 0.97 | NFKB1 (0.64) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Azelaic Acid SCHEMBL11874402 | 0.97 | LMNA (0.68) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Pimelic Acid SCHEMBL2519276 | 0.97 | LMNA (0.68) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Sebacic Acid SCHEMBL11871548 | 0.97 | LMNA (0.68) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Trientine SCHEMBL11876109 | 0.97 | NFKB1 (0.64) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Octanedioate SCHEMBL11875738 | 0.97 | LMNA (0.68) | NFKB1CYP2D6LMNAKMT2ABLM | |
| SCHEMBL8775200 | 0.95 | NFKB1 (0.61) | NFKB1CYP2D6LMNAKMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119505974-A | Rust-proof oil for protecting surface of mechanical part and preparation method thereof | 苏州山河星程材料科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-109369909-B | Cationic wet strength agent and preparation method thereof | 浙江百斯特化工有限公司 | 2021-04-02 | — | — | CN | claimed |
| US-20150322339-A1 | USE OF POLYAMINE AS ANTI-STICKING ADDITIVE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2015-11-12 | — | — | US | claimed |
| CN-103764791-A | Use of polyamine as anti-sticking additive | CONSTR RES & TECH GMBH | 2014-04-30 | — | — | CN | claimed |
| US-8609784-B2 | Water-soluble polyaminoamides as sunscreen agents | NALCO COMPANY (US) | 2013-12-17 | — | — | US | claimed |
| EP-1465957-B1 | CMP SYSTEMS AND METHODS UTILIZING AMINE-CONTAINING POLYMERS | CABOT MICROELECTRONICS CORP (US) | 2006-03-22 | — | — | EP | claimed |
| EP-1241225-B1 | Resins acting as wet strength agents and creping aids and processes for preparing and using the same | HERCULES INC (US) | 2004-11-17 | — | — | EP | claimed |
| EP-1465957-A1 | CMP SYSTEMS AND METHODS UTILIZING AMINE-CONTAINING POLYMERS | Cabot Microelectronics Corporation (US) | 2004-10-13 | — | — | EP | claimed |
| WO-2003062338-A1 | CMP SYSTEMS AND METHODS UTILIZING AMINE-CONTAINING POLYMERS | CABOT MICROELECTRONICS CORPORATION (US) | 2003-07-31 | — | — | WO | claimed |
| US-20030139116-A1 | CMP systems and methods utilizing amine-containing polymers | CABOT MICROELECTRONICS CORPORATION | 2003-07-24 | — | — | US | claimed |
| US-20030114631-A1 | Resins acting as wet strength agents and creping aids and processes for preparing and using the same | HERCULES CORPORATION | 2003-06-19 | — | — | US | claimed |
| EP-1241225-A2 | Resins acting as wet strength agents and creping aids and processes for preparing and using the same | HERCULES INCORPORATED (US) | 2002-09-18 | — | — | EP | claimed |
| US-20010045236-A1 | Fibrous food casings having modified release properties and methods of manufacture | TEEPAK PROPERTIES, LLC | 2001-11-29 | — | — | US | claimed |
| US-H1613-H | TREATING SOLVENT PHASE WITH CAUSTIC TO CONVERT BY-PRODUCTS TO EPICHLOROHYDRIN | HERCULES INCORPORATED (US) | 1996-11-05 | — | — | US | claimed |
| EP-0187451-A2 | Gelled aqueous compositions | HERCULES INCORPORATED (US) | 1986-07-16 | — | — | EP | claimed |
| CN-119505974-A | Rust-proof oil for protecting surface of mechanical part and preparation method thereof | 苏州山河星程材料科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-3724696-B1 | WEEKLY AND MONTHLY DISPOSABLE WATER GRADIENT CONTACT LENSES | ALCON INC (CH) | 2024-07-03 | — | — | EP | disclosed |
| US-3966684-A | RETENTION AIDS FOR PAPER FILLERS | HERCULES INCORPORATED (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966694-A | RETENTION AIDS FOR PAPER FILLERS | HERCULES INCORPORATED (US) | 1976-06-29 | — | — | US | disclosed |
| US-3951921-A | PAPER FILLERS | HERCULES INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |