Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | PLG | P00747 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.62 |
| ▸ | GABRP | O00591 | 1/20 | 0.62 |
| ▸ | GABRD | O14764 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL394243 | 1.00 | NFKB1 (0.67) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL28031081 | 0.97 | NFKB1 (0.64) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL11873219 | 0.97 | NFKB1 (0.64) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL4681431 | 0.97 | NFKB1 (0.64) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Azelaic Acid SCHEMBL11874402 | 0.97 | LMNA (0.68) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Pimelic Acid SCHEMBL2519276 | 0.97 | LMNA (0.68) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Sebacic Acid SCHEMBL11871548 | 0.97 | LMNA (0.68) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Trientine SCHEMBL11876109 | 0.97 | NFKB1 (0.64) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Octanedioate SCHEMBL11875738 | 0.97 | LMNA (0.68) | NFKB1CYP2D6LMNAKMT2ABLM | |
| SCHEMBL8775200 | 0.95 | NFKB1 (0.61) | NFKB1CYP2D6LMNAKMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022709-A1 | HIGHLY BRANCHED WATER-SOLUBLE POLYAMINE OLIGOMERS, PROCESS FOR THEIR PREPARATION AND APPLICATIONS THEREOF | EPOX LTD. (IL) | 2002-03-21 | — | — | WO | disclosed |