SCHEMBL279458

SCHEMBL279458

Cc1ccc(N(c2ccc(CCCO)cc2)c2ccc(-c3ccc(N(c4ccc(CCCO)cc4)c4ccc(C)c(C)c4)c(C)c3)cc2C)cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.38
S1PR1 P21453 1/20 0.36
RARA P10276 1/20 0.34
RARG P13631 1/20 0.34
BACE1 P56817 1/20 0.33
CYP4A11 Q02928 2/20 0.33
MCL1 Q07820 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CHRNA7 P36544 2/20 0.32
CHRNA10 Q9GZZ6 2/20 0.32
CHRNA9 Q9UGM1 2/20 0.32
CYP4F2 P78329 1/20 0.32
CA2 P00918 1/20 0.31
PTAFR P25105 1/20 0.31
BCHE P06276 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11911561 0.93 RARB (0.42) RARBRARARARGBACE1CYP4A11
SCHEMBL438986 0.92 S1PR1 (0.37) RARBS1PR1RARARARGBACE1
SCHEMBL7208250 0.89 RARB (0.42) RARBRARARARGALDH1A1CA2
SCHEMBL12316360 0.87 RARB (0.35) RARBS1PR1MCL1CHRNA7CHRNA10
SCHEMBL8078470 0.86 S1PR1 (0.45) S1PR1MCL1
SCHEMBL11887135 0.86 MCL1 (0.38) RARBS1PR1MCL1
SCHEMBL394254 0.86 S1PR1 (0.42) RARBS1PR1CYP4A11ALDH1A1CYP4F2
SCHEMBL13840022 0.86 S1PR1 (0.42) RARBS1PR1CYP4A11ALDH1A1CYP4F2
SCHEMBL279140 0.85 ALDH1A1 (0.43) RARBMCL1ALDH1A1CYP2D6
SCHEMBL19346857 0.85 HSD11B1 (0.43) RARBALDH1A1CA2BCHECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-20080008944-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2008-01-10 US disclosed
US-20080008944-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2008-01-10 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed