Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946673 | 0.96 | PKM (0.44) | MEN1KMT2ATP53THRBPKM | |
| SCHEMBL3941193 | 0.92 | PKM (0.54) | MEN1KMT2ATP53THRBPKM | |
| SCHEMBL3942037 | 0.90 | TP53 (0.45) | TP53PKM | |
| SCHEMBL3942229 | 0.90 | PKM (0.55) | MEN1KMT2ATP53THRBPKM | |
| SCHEMBL3950668 | 0.89 | TP53 (0.43) | TP53PKM | |
| SCHEMBL3947411 | 0.88 | MEN1 (0.50) | MEN1KMT2APKM | |
| SCHEMBL3945592 | 0.87 | HTT (0.55) | MEN1KMT2ATP53PKMMAPT | |
| SCHEMBL3952033 | 0.87 | HTT (0.55) | MEN1KMT2ATP53PKMMAPT | |
| SCHEMBL3943436 | 0.87 | TSHR (0.46) | HTT | |
| SCHEMBL3942911 | 0.87 | HTT (0.63) | MEN1KMT2APKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |