Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942663 | 0.96 | MEN1 (0.47) | PKMHTTMAPTALDH1A1MEN1 | |
| SCHEMBL3941193 | 0.94 | PKM (0.54) | PKMMMP1MMP2MMP9MMP12 | |
| SCHEMBL3942037 | 0.93 | TP53 (0.45) | PKMTP53 | |
| SCHEMBL3952033 | 0.91 | HTT (0.55) | PKMHTTMAPTALDH1A1MEN1 | |
| SCHEMBL3950668 | 0.91 | TP53 (0.43) | PKMTP53 | |
| SCHEMBL3945592 | 0.90 | HTT (0.55) | PKMHTTMAPTALDH1A1MEN1 | |
| SCHEMBL3943436 | 0.89 | TSHR (0.46) | HTTTSHR | |
| SCHEMBL3945382 | 0.88 | TP53 (0.46) | PKMMMP1MMP2MMP9MMP12 | |
| SCHEMBL3945166 | 0.86 | HTT (0.57) | PKMHTTMAPTALDH1A1MEN1 | |
| SCHEMBL3941781 | 0.86 | TP53 (0.47) | PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |