Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946673 | 0.94 | PKM (0.44) | PKMKMT2AMMP1MMP2MMP9 | |
| SCHEMBL3942663 | 0.92 | MEN1 (0.47) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3942037 | 0.89 | TP53 (0.45) | PKMTP53 | |
| SCHEMBL3944160 | 0.89 | PKM (0.54) | PKMTP53 | |
| SCHEMBL3945068 | 0.88 | PKM (0.61) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3944960 | 0.88 | HTT (0.54) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3950668 | 0.87 | TP53 (0.43) | PKMTP53 | |
| SCHEMBL3952481 | 0.87 | PKM (0.54) | PKMHTT | |
| SCHEMBL3942854 | 0.86 | PKM (0.55) | PKMKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL3952013 | 0.86 | PKM (0.56) | PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |