Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335703 | 1.00 | DNM1 (0.46) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL25844946 | 0.97 | DNM1 (0.50) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL13232029 | 0.97 | DNM1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL14592914 | 0.97 | DNM1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL15188890 | 0.97 | DNM1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL21090668 | 0.95 | DNM1 (0.55) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL25844944 | 0.95 | DNM1 (0.55) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL25844886 | 0.95 | DNM1 (0.55) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL21698622 | 0.95 | DNM1 (0.52) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17035584 | 0.95 | DNM1 (0.52) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180055792-A1 | Polymeric Metformin And Its Use As A Therapeutic Agent And As A Delivery Vehicle | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-01 | — | — | US | disclosed |
| US-9878066-B2 | Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2018-01-30 | — | — | US | disclosed |
| US-20160303517-A1 | DENDRIMER PARTICLES AND RELATED MIXED MATRIX FILTRATION MEMBRANES, COMPOSITIONS, METHODS, AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-10-20 | — | — | US | disclosed |
| US-20150011645-A1 | AMINE DENDRIMERS | GENZYME CORP (US) | 2015-01-08 | — | — | US | disclosed |
| US-20140219951-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |
| US-8158117-B2 | Methods and compositions for phosphate binding | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-04-17 | — | — | US | disclosed |
| US-7767768-B2 | Crosslinked amine polymers | ILYPSA, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100166696-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166696-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | PAM, PHOSPHO1, ARID2 | DNM1 20/4885MEN1 956/4885KMT2A 2130/4885 |
| US-20140219951-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | PAM, ARGLU1, NAAA | DNM1 18/4885MEN1 883/4885KMT2A 2124/4885 |
| US-20180055792-A1 | Polymeric Metformin And Its Use As A Therapeutic Agent And As A Delivery Vehicle | SLC2A8, SLC2A4, SLC2A1 | DNM1 123/4885MEN1 339/4885KMT2A 730/4885 |
| US-20150011645-A1 | AMINE DENDRIMERS | PHOSPHO1, PHPT1, PPIP5K2 | DNM1 111/4885MEN1 284/4885KMT2A 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.