Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941193 | 0.86 | PKM (0.54) | PKMHTTALDH1A1MEN1KMT2A | |
| SCHEMBL3944960 | 0.85 | HTT (0.54) | PKMHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3944160 | 0.85 | PKM (0.54) | PKM | |
| SCHEMBL3952481 | 0.85 | PKM (0.54) | PKMHTTTSHR | |
| SCHEMBL3950731 | 0.85 | PKM (0.38) | PKMHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3944723 | 0.84 | SMN1; SMN2 (0.40) | PKMHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3942715 | 0.83 | RXFP1 (0.48) | PKMHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13941778 | 0.82 | GAA (0.48) | PKMHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3944533 | 0.82 | HTT (0.54) | PKMHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4533026 | 0.82 | PKM (0.52) | PKMHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |