Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 11/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.50 |
| ▸ | ACACB | O00763 | 2/20 | 0.50 |
| ▸ | ACACA | Q13085 | 2/20 | 0.50 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816566 | 0.70 | ALDH1A1 (0.54) | L3MBTL1 | |
| SCHEMBL3638561 | 0.70 | DAO (0.65) | — | |
| SCHEMBL29780995 | 0.70 | DAO (0.65) | — | |
| SCHEMBL6806463 | 0.69 | L3MBTL3 (0.61) | L3MBTL3L3MBTL1TP53BP1MBTD1MEN1 | |
| SCHEMBL6183709 | 0.69 | ACACB (0.84) | L3MBTL3L3MBTL1ACACBACACATP53BP1 | |
| SCHEMBL427533 | 0.68 | MGLL (0.62) | — | |
| SCHEMBL30995232 | 0.68 | ALDH1A1 (0.55) | L3MBTL1MEN1KMT2A | |
| SCHEMBL27669216 | 0.68 | L3MBTL3 (0.94) | L3MBTL3L3MBTL1TP53BP1MBTD1MEN1 | |
| SCHEMBL30194405 | 0.68 | DAO (0.57) | — | |
| SCHEMBL10293557 | 0.68 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1TP53BP1MBTD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010487-A1 | 5-AMIDO-2-CARBOXAMIDE INDOLES | F. Hoffmann-Roche AG (CH) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007115938-A1 | 5-AMIDO-2-CARBOXAMIDE INDOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-10-18 | — | — | WO | disclosed |