Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 17/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159353 | 0.89 | CCR1 (0.73) | CCR1NR1I2 | |
| SCHEMBL2159343 | 0.89 | CCR1 (0.73) | CCR1NR1I2 | |
| SCHEMBL2159338 | 0.89 | CCR1 (0.73) | CCR1NR1I2 | |
| SCHEMBL3949977 | 0.84 | CCR1 (0.78) | CCR1 | |
| SCHEMBL3943882 | 0.83 | DRD2 (0.59) | CCR1DRD2 | |
| SCHEMBL3950425 | 0.79 | CCR1 (0.62) | CCR1 | |
| SCHEMBL3943504 | 0.78 | CCR1 (0.66) | CCR1 | |
| SCHEMBL3940785 | 0.78 | CCR1 (0.56) | CCR1NR1I2 | |
| SCHEMBL5045757 | 0.78 | CCR1 (0.54) | CCR1DRD2 | |
| SCHEMBL13676795 | 0.77 | CCR1 (0.59) | CCR1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049486-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007092681-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |